Chlamydia Trachomatis



venerealdiseaseabout.blogspot.com - His time we discuss one of the causes of genital Chlamydia trachomatis desease, and this is partially from information:

Order  : Chlamydiales
Family  : Chlamydiaceae
Genus  : Chlamydia

Chlamydia trachomatis is an obligate intracellular bacterial pathogen, one of three species of bacteria in the genus Chlamydia. C. trachomatis is a Gram negative, reddish look under the microscope after stained with Gram stain.

C. trachomatis intracytoplasmic inclusion bodies form a dense and contain glycogen. Generally sensitive to sulfonamides. In humans can cause disease trachoma, inclusion conjunctivitis, nonspecific urethritis, salpingitis, cervicitis, pneumonitis in infants, and lymphogranuloma venerum.  

Development  Cycle and  Pathogenesis
Chlamydia evolved through several stages. Start with the infectious elementary body, spherical with a diameter from 0.2 to 0.4 microns, has a core and a number of ribosomes covered by a cell wall composed of several layers. Elementary bodies enter into cells by phagocytosis. Vacuole formed around him. Within 8 hours of elementary bodies grown to the size of the initial weight from 0.8 to 1.5 microns. This form is also referred to as the reticular body, the cell contents are less dense than the elementary body, 4x RNA levels more than DNA and are not infectious.

Four hours following the initial weight binary divide, forming the intermediate body and then elementary body. Intermediate entity is a transitional form between the initial and elementary body weight. Agency initials, intermediate bodies and elementary bodies accumulated in the vacuoles role in the cell, thus referred to as a form of inclusion bodies. Inclusion bodies are bacteria microcolonies inside host cells. In the host cells can form germ few microcolonies phagocytosis in case of more than one elementary body. Maturation initials into elementary body weight is accompanied by increased synthesis of DNA so that DNA and RNA levels balanced. At the time of host cells rupture, the elementary body out and cause infection in the new host cells. Chlamydia developmental cycle takes 24-48 hours.

Sources: E. Jawetz, Microbiology





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1 comments:

Anonymous said...

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